Measuring the effect of amantadine in chronic anoxic minimally conscious state.
نویسندگان
چکیده
منابع مشابه
Vegetative state and minimally conscious state: a review of the therapeutic interventions.
BACKGROUND/AIMS The purpose of the present article is a systematic review of the proposed medical or surgical treatments in patients in chronic vegetative state (VS) or minimally conscious state (MCS), as well as of their mechanisms of action and limitations. METHODS For this review, we have agreed to include patients in VS or MCS having persisted for over 6 months in posttraumatic cases, and...
متن کاملPlacebo-controlled trial of amantadine for severe traumatic brain injury.
BACKGROUND Amantadine hydrochloride is one of the most commonly prescribed medications for patients with prolonged disorders of consciousness after traumatic brain injury. Preliminary studies have suggested that amantadine may promote functional recovery. METHODS We enrolled 184 patients who were in a vegetative or minimally conscious state 4 to 16 weeks after traumatic brain injury and who w...
متن کاملChanges in cerebral metabolism in patients with a minimally conscious state responding to zolpidem
BACKGROUND Zolpidem, a short-acting non-benzodiazepine GABA agonist hypnotic, has been shown to induce paradoxical responses in some patients with disorders of consciousness (DOC), leading to recovery of arousal and cognitive abilities. We here assessed zolpidem-induced changes in regional brain metabolism in three patients with known zolpidem response in chronic post-anoxic minimally conscious...
متن کاملWillful Modulation of Brain Activity in Disorders of Consciousness
To the Editor: The report by Monti et al. (Feb. 18 issue)1 has raised concern worldwide among relatives of patients in a persistent vegetative state. Could their loved ones be conscious after all? However, in addressing such concerns, perhaps the mechanism of brain injury should be considered. It is worthwhile noting that all five patients who were in a vegetative or minimally conscious state a...
متن کاملP24: Minimally Conscious State Improvements with Thalamic Ventralis Intermedius Nucleus Stimulation after Severe Traumatic Brain Injury
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عنوان ژورنال:
- Journal of neurology, neurosurgery, and psychiatry
دوره 79 2 شماره
صفحات -
تاریخ انتشار 2008